Professor Ruby Yun-Ju Huang

Professor, School of Medicine & Graduate Institute of Oncology, College of Medicine, National Taiwan University

Professor Ruby Yun-Ju Huang is a renowned clinician scientist in the international ovarian cancer (OC) research and the field of EMT (epithelial-mesenchymal transition). As a clinician-scientist, her research interest is in the plasticity of biological systems. In the field of EMT, she is best known to define the early events of EMT and to propose the paradigm shift of the EMT concept from binary to a continuous spectrum. She utilizes ovarian cancer as the working model to decipher the role of EMT spectrum in tumoral heterogeneity to understand how this EMT spectrum is regulated at the 3D genome, epigenome, transcriptome, proteome, and functional levels. Her recent work extends to the identification of epithelial and mesenchymal subtypes and the immune features of ovarian clear cell carcinoma (OCCC), and Asian dominant disease. She is also a pioneer of spatial omics research in Asia.